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Bring Your Own PK/PD Model13 days ago
1. A minimal conversion | 2. What conversion actually does | 3. $OMEGA coexistence | 4. The lp/hazard boundary | 5. Compile cost and caching
Joint PK/PD and Time-to-Event Simulation13 days ago
1. What this is for | 2. Library models | 3. Covariates and the linear predictor | Where a covariate ends and a model parameter begins | Combining dosing data with covariates | 4. Between-subject variability | 5. Beyond this tour | 6. Accuracy, messages, and when things get slow | 7. Backward compatibility
Censoring and Realistic Assessment Schedules2 months ago
1. Right censoring | Choosing the censoring rate for a target censoring fraction | 2. Interval censoring | Left censoring | Delayed entry (not implemented) | 3. Realistic visit schedules | Missed visits and assessment dropout | Informative assessment schedules
Advanced Simulation Scenarios2 months ago
Exploring the Prognostic Index | Visualisation | Custom mrgsolve Models with sim_tte_df | Event-Time Interpolation | Multiple Treatment Arms
Getting Started with simtte2 months ago
Introduction | Statistical Framework | Weibull Model | M-Spline Model | Inverse Transform Sampling | Basic Workflow | Weibull Example | M-Splines Example | Event-Time Interpolation | Output Structure | References